Table 3. Combined genotype frequencies among the case patients and control subjects and their collection to clear cell renal cell carcinoma.
| Variables | Case (n = 859) | Controls (n = 1005) | P-valuea | Adjusted OR (95% CI)b | ||
| n | % | n | % | |||
| rs706209 and rs9332 | ||||||
| Number of risk allele | ||||||
| 0 | 304 | 35.4 | 286 | 28.5 | ||
| 1 | 358 | 41.7 | 432 | 43.0 | 0.022 | 0.79(0.64–0.99) |
| 2 | 171 | 19.9 | 237 | 23.6 | 0.003 | 0.68(0.52–0.88) |
| 3 | 26 | 3.0 | 49 | 4.9 | 0.006 | 0.48(0.29–0.81) |
| 4 | 0 | 0 | 1 | 0 | ||
| Recombined groups | ||||||
| 0 | 304 | 35.4 | 286 | 28.5 | ||
| 1–4 | 555 | 64.6 | 719 | 71.5 | 0.001 | 0.73(0.06–0.90) |
a
Two-sided χ2 test for the distributions of genotypes.
b
Adjusted for age, gender, BMI, smoking status, drinking status, hypertension and diabetes in logistic regression model.