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. Author manuscript; available in PMC: 2013 Nov 22.
Published in final edited form as: JAMA Pediatr. 2013 Jan;167(1):10.1001/jamapediatrics.2013.419. doi: 10.1001/jamapediatrics.2013.419

Table 5.

Proportion of Cases and Costs Identified for the Different Screening Strategies for a 25% Increase in Prevalence, a 25% Decrease in Prevalence, or Adult Prevalence Assumptions

Screening Strategy and Cutoff Value Cases Identified, % 25% Increase in Prevalence
25% Decrease in Prevalence
Adult Prevalence Assumptions (8% for Diabetes and 37% for Prediabetes)
Total Costs (Direct and Indirect), $ Cost per Case Identified (Direct and Indirect), $ Total Costs (Direct and Indirect), $ Cost per Case Identified (Direct and Indirect), $ Total Costs (Direct and Indirect), $ Cost per Case Identified (Direct and Indirect), $
Diabetes mellitus
 2-h OGTT(200mg/dL) 100 156111876 249779 156111876 416298 156111876 781
 HbAlc
 5.5% 33 138513150 664 930 138514325 1108225 137576050 2064
 5.7% 33 121958377 585459 121957896 975 761 122 341851 1835
 6.5% 33 95216051 457 083 95 212895 761 779 97732 759 1466
Dysglycemia (prediabetes and diabetes)
 2-hOGTT(140mg/dL) 100 156111876 312 156111876 520 156111876 169
Random glucose test
 100mg/dL 55 110385806 401 108517621 658 114 355 700 225
 110mg/dL 30 87245787 582 85 717272 952 90493 882 326
HbA1c
 5.5% 45 137454618 611 137284783 1017 137815518 331
 5.7% 32 120258824 752 119749319 1247 121341523 410
 6.5% 7 94 571280 2702 94146693 4483 95 473 529 1474
1-h Glucose challenge test
 110mg/dL 63 145118357 461 142 910502 756 149810049 257
 120mg/dL 44 125 799626 572 123 676688 937 130310868 326

Abbreviations: HbA1c hemoglobin A1c; OGTT, oral glucose tolerance test.

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