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. Author manuscript; available in PMC: 2013 Nov 22.
Published in final edited form as: Angew Chem Int Ed Engl. 2010;49(2):10.1002/anie.200905223. doi: 10.1002/anie.200905223

Scheme 1.

Scheme 1

Projected diastereo- and enantioselective synthesis of nyasol through Cu-catalyzed allylic alkylation with a cis vinylaluminum reagent. NHC=N-heterocyclic carbene, PG=protecting group.