Table 1.
Characteristics of the Study Population.
| Overall population (n=176) | Normal glucose tolerance (n=105) | Dysglycemia (n=71) | p-Value | |
|---|---|---|---|---|
| Mean (SD) age | 13.7 (2.1) | 13.6 (2.1) | 13.7 (2.0) | 0.93 |
| Sex, % (n) | ||||
| Female | 50.0 (88) | 56.2 (59) | 40.9 (29) | |
| Male | 50.0 (88) | 43.8 (46) | 59.1 (42) | 0.05 |
| Race,%(n) | ||||
| White | 59.7 (105) | 65.7 (69) | 50.7 (36) | |
| Black | 31.8 (56) | 27.6 (29) | 38.0 (27) | |
| Other | 8.5 (15) | 6.7 (7) | 11.3 (8) | 0.13 |
| Weight status, % (n) | ||||
| Overweight (BMI ≥85th and <95th percentiles) | 17.6 (31) | 24.8 (26) | 7.0 (5) | |
| Obese (BMI ≥95th percentile) | 82.4 (145) | 75.2 (79) | 93.0 (66) | <0.01 |
| Family history of T2 D, % (n) | ||||
| First-degree relative | 25.6 (45) | 18.1 (19) | 36.6 (26) | |
| Second-degree relative | 46.0 (81) | 46.7 (49) | 45.1 (32) | |
| No family history | 28.4 (50) | 35.2 (37) | 18.3 (13) | <0.01 |
| Self-report of hyperlipidemia, % (n) | 11.4 (20) | 12.4 (13) | 9.9 (7) | 0.61 |
| Self-report of PCOSa, % (n) | 3.4 (3) | 1.7 (1) | 6.9 (2) | 0.21 |
| Maternal history of diabetes, %(n) | 10.8 (19) | 8.6 (9) | 14.1 (10) | 0.25 |
| % Abnormal BP (14), % (n) | 29.0 (51) | 28.6 (30) | 29.6 (21) | 0.89 |
| % Abnormal BP using modified guidelines (15), % (n) | 42.1 (74) | 42.9 (45) | 40.9 (29) | 0.79 |
| Presence of acanthosis nigricans, % (n) | 10.2 (18) | 2.9 (3) | 21.1 (15) | <0.01 |
| Tanner stageb (n=134), % (n) | ||||
| 1 | 7.5 (10) | 7.3 (6) | 7.7 (4) | |
| 2 | 11.9 (16) | 12.2 (10) | 11.5 (6) | |
| 3 | 22.4 (30) | 24.4 (20) | 19.2 (10) | |
| 4 | 32.1 (43) | 30.5 (25) | 34.6 (18) | |
| 5 | 26.1 (35) | 25.6 (21) | 26.9 (14) | 0.97 |
| Median (range) Tanner stage | 4 (1–5) | 4 (1–5) | 4 (1–5) | |
| Pubertal, % (n) | 92.5 (124) | 92.7 (76) | 92.3 (48) | |
| Prepubertal, % (n) | 7.5 (10) | 7.3 (6) | 7.7 (4) | 0.94 |
| Mean (SD) random glucose, mg/dL | 97.7 (16.6) | 92.9 (13.7) | 104.8 (18.0) | <0.001 |
| Mean (SD) 1-h glucose challenge test | 113.3 (28.7) | 104.0 (22.0) | 127.0 (32.0) | <0.001 |
| Mean (SD) HbA1c, % | 5.5 (0.5) | 5.5 (0.4) | 5.6 (0.5) | 0.11 |
a
Prevalence among females only.
b
For those with self-reported pubertal measures (n=134).