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. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: J Mol Cell Cardiol. 2013 Sep 10;64:10.1016/j.yjmcc.2013.09.001. doi: 10.1016/j.yjmcc.2013.09.001

Figure 1.

Figure 1

Panel A: Representative action potentials recorded from ventricular epicardial, midmyocardial and endocardial tissue slices isolated from the 2 week old neonate. Action potentials lack a spike and dome morphology and are of comparable duration. BCL= 2 s. Panel B: Application of an IKs inhibitor (chromanol 293B, 30 μM) failed to alter action potential duration. Panel C: Application of an IKr inhibitor (d-sotalol, 100 μM) produced a very significant homogeneous prolongation of APD in all 3 cell types.