Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Effects of IKs and IKr Inhibitors on Tissue Layers from 2-week Neonates
| Control (APD90) | Chromanol (APD90) | % Increase | Incidence of EAD | |
|---|---|---|---|---|
| Epi- | 182±13 (n=5) | 206±12 (n=5) | 15±8 | 0/5 |
| Mid- | 203±13 (n=4) | 208±8 (n=4) | 4±3 | 0/4 |
| Endo- | 207±8 (n=4) | 233±25 (n=4) | 12±8 | 0/4 |
| Control (APD90) | Sotalol (APD90) | % Increase | Incidence of EAD | |
|---|---|---|---|---|
| Epi- | 190±10 (n=4) | 274±27 (n=4)* | 45±7* | 0/4 |
| Mid- | 208±8 (n=5) | 297±22 (n=5)* | 43±6* | 0/5 |
| Endo | 232±8 (n=4) | 356±20 (n=4)* | 53±7* | 0/4 |
significantly different from control at p<0.05
