Fig 2.

Enhanced CVB3-specific mucosal immune responses with coimmunization with pHMGB1. (A) Serum IgG titers. (B) Fecal SIgA titers. (C) Serum IgG neutralizing antibody (Ab) titers. (D) Fecal SIgA neutralizing antibody titers. (E) T cell proliferation responses in MLNs. (F) Frequency of IFN-γ-secreting cells in MLNs. Each group contained 8 mice. Experiments were repeated three times, with similar results. All of the experimental data were pooled and are presented together. OD, optical density; SFC, spot-forming cells. ∗, P < 0.05.