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Summary of steady-state kinetic data for the deamination of dA, EdA, and CNdA by ADAa
| Compound (no.) | Mean Km ± SD (μM) | kcat (s−1) | kcat/Km (s−1 · μM−1) |
|---|---|---|---|
| dA (1) | 42.6 ± 15.0 | 13.5 | 0.32 |
| EdA (3) | 145.9 ± 37.6 | 11.3 | 0.08 |
| CNdA (7) | 156.9 ± 84.2 | 8.9 | 0.06 |
Data were determined spectrophotometrically.
