Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
In vivo isavuconazole dose-response curves for multiple A. fumigatus isolates. The prodrug (BAL8557) was administered in 2-fold increasing concentrations of 40 to 640 mg/kg by the OG route every 12 h for 7 days. Open symbols represent wild-type isolates, and closed symbols represent cyp51 mutants. Each symbol represents the geometric mean organism burden ± the standard deviation as measured by qPCR.
