Table 7.

Monte Carlo simulation predictions of treatment success rates for several amoxicillin regimens in pregnant and postpartum women and in children

Amoxicillin regimen	Success rate (%) in:
	Women			Children
	Second trimester of pregnancy	Third trimester of pregnancy	3 mo postpartum
1,000 mg q 8 h	35.8	33.0	55.6
500 mg q 6 h	32.8	30.6	54.4
750 mg q 6 h	48.2	50.7	65.3
1,000 mg q 6 h	63.2	73.4	69.7
45 mg/kg/day (15 mg/kg q 8h)				38.4
90 mg/kg/daya
30 mg/kg q 8 h				43.8
22.5 mg/kg q 6 h				43.4

^aThis dosage is twice the ACIP recommendation of 45 mg/kg/day; 90 mg/kg/day has been given to children with otitis media (5, 34).