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Viable counts of the quinolone-susceptible E. coli CFT073-RR (A) and the three isogenic derivative strains (E. coli CFT073-RR/p449 [B], E. coli CFT073-RR GyrAr [C], and E. coli CFT073-RR GyrAr/p449 [D]) in in vitro time-kill assays with ciprofloxacin concentrations at 1×, 2×, and 4× the MIC.
