Table 1.
Characteristics of clonal parasite lines binding to CD36 under flow conditions
| Parasite clone | var gene | No. of domains | % pRBCs remaining | Median rolling velocitya (5% CI) (μm s−1) | Elongation indexb (5% CI) (%) | % Remaining rankc | Rolling-velocity rankd |
|---|---|---|---|---|---|---|---|
| ItG 1E7 | var31 | 4 | 71.3 | 2.31 (2.25–2.36) | 2.0 (1.7–2.3) | 1 | 1 |
| 3G8 | var1 | 6 | 67.6 | 3.38 (3.26–3.50) | 9.3 (8.8–9.8) | 2 | 2 |
| P3G5 | var10 | 4 | 57.4 | 4.62 (4.09–5.14) | 12.9 (12.3–13.6) | 4 | 3 |
| var32 | 5 | ||||||
| P6G2 | var31 | 4 | 58.7 | 5.06 (4.90–5.23) | 9.1 (8.7–9.3) | 3 | 4 |
| P4H12 | var44 | 5 | 31.4 | 7.13 (6.24–8.02) | 9.3 (8.3–10.3) | 7 | 5 |
| P6D12 | var39 | 4 | 42.9 | 7.83 (7.59–8.06) | 11.3 (11.0–11.6) | 5 | 6 |
| var67 | 5 | ||||||
| P2E11 | var33 | 4 | 40.2 | 10.3 (10.1–10.4) | 7.6 (7.3–7.8) | 6 | 7 |
| P6A1 | var11 | 5 | 9.6 | 11.3 (11.0–11.6) | 8.9 (8.6–9.3) | 8 | 8 |
a
Median rolling velocity was calculated at 1.6-Pa WSS.
b
Elongation index was calculated at 1.6-Pa WSS.
c
Percent remaining rank is the percentage of adherent parasites remaining by the end of the decreasing WSS measurement. Parasites are ranked in descending order.
d
Rolling-velocity rank is the median rolling velocity in ascending order. The 5% confidence interval (CI) about the median is given.