Fig 2.

Immunization reduces bacterial burden in vaccinated mice at 72 h after challenge. Bacterial burden in lung, spleen, and liver tissues was determined in naive and vaccinated mice (n = 5) 72 h after intranasal challenge with B. pseudomallei strain 1026b. Statistical comparisons between vaccinated and naive groups were done using a nonparametric t test. *, P < 0.05. Similar results were obtained in one additional experiment.