Fig 6.

Effects of epithelial β-catenin (βcat) depletion on amelogenesis, EMT, and cementogenesis. P42 WT or BKO teeth were examined with μCT scanning (A and F), backscatter SEM (B), or IHC for Krt5 (E). P7 WT or BKO teeth were examined with ISH for Amelx (C), Col1a1 (D), and Krt14 (E). (G to I) WT and BKO DEpSCs were induced as described in the legend to Fig. 4 and analyzed with qRT-PCR for expression of genes related to amelogenesis or cementogenesis (G), EMT (H), and the Bmp pathway (I) (n = 3 and P < 0.05 for all genes except E-cad).