Table 5.
Sensitivities and specificities of VL-RDTs of stored samples tested in the reference laboratory BHU, Varanasi, India
| Product | Sensitivity (n [%]) (95% CI) for sample type: |
Specificity (n [%]) (95% CI) for sample type: |
||
|---|---|---|---|---|
| Blood (n = 150) | Serum (n = 150) | Blood (n = 119) | Serum (n = 119) | |
| Signal-KA | 145 (96.7) (92.4, 98.9) | 147 (98.0) (94.3, 99.6) | 114 (95.8) (90.5, 98.6) | 117 (98.3) (94.1, 99.8) |
| Crystal-KA | 148 (98.7) (95.3, 99.8) | 149 (99.3) (96.3, 100.0) | 118 (99.2) (95.4, 100.0) | 113 (95.0) (89.4, 98.1) |
| Onsite Leishmania Ab (RevA) rapid test | 142 (94.7) (89.8, 97.7) | 145 (96.7) (92.4, 98.9) | 117 (98.3) (94.1, 99.8) | 110 (92.4) (86.1, 96.5) |
| Onsite Leishmania Ab (RevB) rapid test | 149 (99.3) (96.3, 100.0) | 149 (99.3) (96.3, 100.0) | 63 (52.9) (43.6, 62.2) | 60 (50.4) (41.1, 59.7) |
| Kala-azar Detect | 150 (100) (97.6, 100.0) | 149 (99.3) (96.3, 100.0) | 114 (95.8) (90.5, 98.6) | 115 (96.6) (91.6, 99.1) |
| DiaMed-IT LEISH | 149 (99.3) (96.3, 100.0) | 148 (98.7) (95.3, 99.8) | 117 (98.3) (94.1, 99.8) | 112 (94.1) (88.3, 97.6) |