Table 2.
Sensitivities, specificities, and predictive values for CT detection by CT-RTCA, VET-RPLA, and real-time PCR assays
| Type | Assay | No. of isolates/stool specimensa |
Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | |||
|---|---|---|---|---|---|---|---|---|---|
| S+ T+ | S+ T− | S− T+ | S− T− | ||||||
| Strain | CT-RTCA | 77 | 2 | 0 | 121 | 97.5 | 100.0 | 100.0 | 98.4 |
| VET-RPLA | 61 | 18 | 0 | 121 | 77.2 | 100 | 100.0 | 87.1 | |
| Real-time PCR | 79 | 0 | 22 | 99 | 100.0 | 81.8 | 78.2 | 100.0 | |
| Stool | CT-RTCA | 27 | 3 | 2 | 68 | 90.0 | 97.2 | 93.1 | 95.8 |
| VET-RPLA | 17 | 13 | 1 | 69 | 56.7 | 98.6 | 94.4 | 84.1 | |
| Real-time PCR | 30 | 0 | 6 | 64 | 100.0 | 91.4 | 83.3 | 100.0 | |
| Total | CT-RTCA | 104 | 5 | 2 | 189 | 95.4 | 99.0 | 98.1 | 97.4 |
| VET-RPLA | 78 | 31 | 1 | 190 | 71.6 | 99.5 | 98.7 | 86.0 | |
| Real-time PCR | 109 | 0 | 28 | 163 | 100.0 | 85.3 | 79.6 | 100.0 | |
a
S, standard; T, test (CT-RTCA, VET-RPLA or real-time PCR assay); +, positive; −, negative; PPV, positive predictive value; NPV, negative predictive value.