Table 2.
MAb | Epitopea |
|
---|---|---|
FL residues only | FL and bc loop residues | |
MAbs derived from primary DENV infection | ||
DVD19.4 | 101, 106, 108 | |
DVD19.13 | 101, 106, 108 | |
DVD23.3 | 101, 106 | |
DVD23.4 | 101, 106 | |
DVB64.31 | 101, 106, 107, 108 | |
DVC23.13 | 101, 108 | |
DVG6.3 | 101, 108 | |
DVG7.5 | 101, 108 | |
DVG1.3 | 107 | |
DVG12.2 | 107, 108, 76 | |
DVD26.3 | 101, 107, 108, 78 | |
DVD26.11 | 101, 107, 108, 78 | |
MAbs derived from secondary DENV infection | ||
749B4 | 101, 107, 108 | |
749B12 | 101, 107, 108 | |
753C1 | 101, 107, 108 | |
751A1 | 101, 107, 108 | |
751B11 | 101, 106, 108 | |
751B12 | 101, 106, 108 | |
750D7 | 101, 106, 108 | |
749B2 | 101, 106, 107, 108 | |
751C4 | 101, 106, 107, 108 | |
751A2 | 101, 106, 107, 108 | |
751B3 | 101, 106, 107, 108 | |
749B6 | 101, 108 | |
753A1 | 101 | |
750C9 | 101 | |
751B6 | 101, 108, 78 | |
753C6 | 101, 106, 107, 108, 76 | |
751C10 | 101, 106, 107, 108, 76, 78 | |
753C8 | 101, 106, 107, 108, 76 | |
753C12 | 101, 107, 108, 76 | |
751A12 | 101, 107, 108, 76 |
Epitopes were identified by a previously described dot blot assay, VLP-capture ELISA, and structure-based analysis (19).