Fig 1.

Identification of CD4⁺ T cell epitopes within YFV proteins. (A) Staining of in vitro-stimulated cells from an HLA-DRB1*03:01 vaccinee with tetramers (Tmer) loaded with peptide pools spanning the YFV envelope protein. Peptide pools 2 and 12 contained DRB1*03:01-restricted epitopes. (B) Identification of the antigenic peptide within envelope pool 2 by staining of in vitro-stimulated cells with tetramers loaded with single peptides. The pool 2 epitope was identified within the Env 43-59 peptide.