Fig 7.

Treatment with AS1411 results in decreased titers of DENV. (A) Virus titers from HEK293 cells infected with DENV (MOI, 0.1) and treated with AS1411 at 1 μM, 3 μM, 4 μM, 5 μM, or 7 μM or with negative-control CRO at 7 μM per ml. Samples were collected at 72 h postinfection, and the titers were determined in duplicate on Vero cells (P < 0.01). (B) Virus titers from HEK293 cells infected with DENV (MOI, 3), followed by treatment with AS1411 or the NC. Samples were collected at time zero and at 24-h intervals for 72 h postinfection. The titers of samples were determined in duplicate on Vero cells. The data are representative of three independent experiments (P < 0.01). The error bars indicate SD.