Fig 1.

Phenotype of T and NK cells in relation to CMV and EBV serostatus. PBMC from CMV⁻ (n = 13) and CMV⁺ (n = 32) 5-year-old children were phenotyped ex vivo. (A) Representative example of flow cytometric gating of viable CD14⁻ CD19⁻ CD8⁺ CD3⁺ and CD14⁻ CD19⁻ CD3⁻ CD56^dim lymphocytes for the proportion of CD57 and NKG2C expressing cells. (B to K) Proportions of CD57⁺ CD8⁺ T cells (B and F), NKG2C⁺ NK cells (C and G), CD57⁺ NKG2C⁺ NK cells (D and H), CD57^bright NKG2C⁺ NK cells (E and I), and) NKG2A⁺ NKG2C⁺ NK cells (J and K) in CMV⁻ and CMV⁺ groups and after subdivision with regard to EBV serostatus. (L and M) Spearman analysis of correlation between the proportions of CD57⁺ CD8⁺ T cells and NKG2C⁺ NK cells (L) or between CD57⁺ CD8⁺ T cells and CD57⁺ NKG2C⁺ NK cells (M). Filled circles depict outlier values.