Fig 4.

EBV infection in vitro induces NKG2C⁺ NK cell enrichment. PBMC from 5-year-old CMV⁺ children (n = 3 to 5) were subjected to in vitro EBV infection and cultured for 14 days, when the NK cell population was phenotyped by flow cytometry. (A) Gating strategy for NKG2C expression on CD3⁻ CD19⁻ CD56^dim cells. (B and C) Percentages of NKG2C⁺ CD56^dim NK cells on day 7 (B) and day 14 (C) postinfection. (D) Percentage of CD57⁺ NKG2C⁺ CD56^dim NK cells on day 14 postinfection. Numbers in the diagrams indicate the fold change that was calculated by dividing the values from infected cultures by those for noninfected cultures.