Table 2.

Histological results of the evaluation of the Mankin score and Otte score according to regional affiliations of the samples and the grade of cartilage lesion classified by ICRS.

Localization	ICRS	General	Femoral	Tibial	Patellar
Mankin score	0	5.5(--) [1]	5.5 (--) [1]	--[0]	--[0]
	1	5.5 (0.7) [22]**	5.4 (0.5) [21]**	6.0 (--)[1]**	--[0]
	2	7.5 (0.4) [23]**	7.4 (0.6) [16]**	9.0 (0.2) [5]**	4.5 (1.4) [2]**
	3	9.5 (0.3) [20]**	9.9 (0.3) [10]**	9.0 (0.3) [9]	10.0 (--) [1]**
Otte score	0	1 (--) [1]	1 (--)[1]	--[0]	--[0]
	1	1.2 (0.2) [22]**	1.1 (0.7) [21]**	1 (--)[1]**	--[0]
	2	1.9 (0.2) [23]**	1.9 (0.7) [16]**	2.4 (0.5) [5]**	1.5 (0.7) [2]**
	3	2.7 (0.1) [20]**	2.9 (0.6) [10]**	2.4 (0.5) [9]	3 (--)[1]**

Data are expressed as means, standard deviation and total of samples.

^*Significant change at a level of P < 0.05;

^**significant change at a level of P < 0.001