Table 2. Patients groups from plasma samples included in this study according to revised ESPGHAN criteria.
Study patients | n | Children | Adults | HLA DQ2/DQ8 | IgA-tTG/EMA | Atrophy grade at diagnosis (Marsh criteria) | |
---|---|---|---|---|---|---|---|
Celiac patients | aCD-patient | 47 | 31 | 16 | + | + | II-III |
GFD-patient | 29 | 17 | 12 | + | + | II-III | |
Non-Celiac patients | C-individual | 37 | 10 | 27 | +/- | - (*) | N.D |
GP-patient | 69 | 23 | 46 | +/- | - (*) | N.D/M.M |
Active celiac disease (aCD-patients), celiac disease on a gluten-free diet (GFD-patients), healthy controls (C-individuals) and other gastrointestinal pathology (GP-patients).
Serological test were performed only in genetically susceptible patients.
N.D = Not determined.
M.M = Mild mucosal alterations non compatibles with CD.