Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2013 Nov 22;8(11):e80923. doi: 10.1371/journal.pone.0080923

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2013 Holter et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

HdhQ111/+ and Hdh+/+ mice at 46 weeks of age were tested on an automated CatWalk system (A-D) and for their ability to descend a vertical pole (E,F). HdhQ111/+ mice showed reduced Right by Left hindlimb stride length (A,B), a decreased cruciate step pattern frequency of pattern left front-right front-left hind-right hind (C,D) and an increased time to descend a vertical pole (total duration being the time taken to turn at the top of the pole and descend to the bottom). . For the CatWalk N=10 per sex and genotype; for the pole descent, males N=8 Hdh+/+, N=9 HdhQ111/+, females N=10 per genotype. Plotted are Tukey box-whisker graphs. All tests showed a significant genotype p value in a 2-way ANOVA. * Adjusted p value (p<0.05) following multiple testing correction.