Figure 4. Exposure to CS decreased levels of the anti-apoptotic Bcl-2 and Mcl-1 molecules in macrophages.

THP-1 macrophages were exposed to CS at concentrations of 1, 5 and 10 μg/ml for 24 h, then the macrophages were infected with Mtb. Relative units of Bcl-2 (A) and Mcl-1 (B) are shown; band densities in the Western Blots were normalized against GAPDH. One of the four independent Western Blots for Bcl-2 and Mcl-1 (C) is represented. Bars indicate mean ± SD. *P<0.05. ANOVA and Dunnett’s post-hoc test compared to unexposed macrophages.