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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Pathog Dis. 2013 Aug 19;69(3):10.1111/2049-632X.12067. doi: 10.1111/2049-632X.12067

Table 2.

Immunological and Virological changes in different IC groups during followup

Category Baseline 3rd Month 6th Month 9th Month 12th Month
Total N a (Nd) 52(62) 52(58) 52(58) 52(53) 52(52)
DC % 0.36 ± 0.03 0.29 ± 0.02 0.39 ± 0.03 0.41 ± 0.02 0.49 ± 0.03
Cells/mm3 31 ± 2 25 ± 2 34 ± 3 34 ± 2 40 ± 3
mDC % 0.26 ± 0.02 0.22 ± 0.02 0.29 ± 0.02 0.3 ± 0.02 0.38 ± 0.03
Cells/mm3 22 ± 2 18 ± 1 25 ± 2 25 ± 1.41 31 ± 2
pDC % 0.1 ± 0.01 0.07 ± 0.01 0.10 ± 0.01 0.11 ± 0.01 0.11 ± 0.01
Cells/mm3 9 ± 1 6 ± 1 9 ± 1 9 ± 1 9 ± 1
CD3 % 79 ± 10 81 ± 2 81 ± 1 82 ± 1 79 ± 2
Cells/mm3 2878 ± 1439 3100 ± 198 2963 ± 195 3093 ±154 2901 ± 172
CD4 % 21 ± 4 25 ± 2 26 ± 1 28 ± 2 26 ± 1
Cells/mm3 766 ± 374 947 ± 63 958 ± 80 1048 ± 77 867 ± 66
CD8 % 53 ± 10 51 ± 2 50 ± 1.6 50 ± 1.92 49 ± 2
Cells/mm3 1909 ± 1041 1953 ± 143 1820 ± 133 1880 ± 111 1694 ± 125
VL (Log10) copies/ml 4.94 -- 4.42 -- 4.31
IC1 N a (Nd) 18(20) 18(20) 18(20) 18(18) 18(18)
DC % 0.31 ± 0.13 0.30 ± 0.15 0.36 ± 0.14 0.43 ±0.23 0.53 ± 0.26
Cells/mm3 27 ± 14 25 ± 15 32 ± 19 35 ± 15 42 ± 22
mDC % 0.24 ± 0.09 0.23 ± 0.14 0.28 ± 0.12 0.34 ± 0.2 0.43 ± 0.23
Cells/mm3 21 ± 11 19 ± 13 24 ± 12 27 ± 12 34 ± 18
pDC % 0.07 ± 0.05 0.07 ± 0.03 0.08 ± 0.05 0.09 ± 0.04 0.10 ± 0.06
Cells/mm3 6 ± 4 6 ± 3 8 ± 7 7 ± 4 8 ± 5
CD3 % 79 ± 8 83 ± 7 82 ± 6 81 ± 6 78 ± 9
Cells/mm3 2954 ± 1079 2736 ± 870 2789 ± 1410 2743 ± 1073 2365 ± 774
CD4 % 32 ± 5 33 ± 7 31 ± 5 34 ± 7 34 ± 8
Cells/mm3 1213 ± 530 1086 ± 395 1068 ± 619 1150 ± 549 1033 ± 448
CD8 % 42 ± 8 46 ± 9 46 ± 9 43 ± 11 40 ± 11
Cells/mm3 1557 ± 578 1517 ± 548 1560 ± 802 1461 ± 703 1197 ± 437
VL (Log10) copies/ml 4.7 -- 4.73 -- 4.53
IC2 N a (Nd) 22(33) 22(25) 22(25) 22(22) 22(22)
DC % 0.38 ± 0.28 0.27 ± 0.15 0.43 ± 0.24 0.38 ± 0.10 0.49 ± 0.25
Cells/mm3 31 ± 17 22 ± 12 30 ± 12 35 ± 11 40 ± 22
mDC % 0.26 ± 0.20 0.2 ± 0.13 0.32 ± 0.21 0.26 ± 0.07 0.39 ± 0.21
Cells/mm3 22 ± 13 17 ± 9 22 ± 8 24 ± 9 31 ± 13
pDC % 0.12 ± 0.10 0.07 ± 0.05 0.10 ± 0.05 0.12 ± 0.06 0.10 ± 0.07
Cells/mm3 10 ± 6 6 ± 4 8 ± 5 11 ± 4 9 ± 6
CD3 % 78 ± 7 80 ± 9 79 ± 9 82 ± 9 79 ± 12
Cells/mm3 2899 ± 1374 3546 ± 2039 2639 ± 1243 3608 ± 1237 2830 ± 1316
CD4 % 21 ± 3 21 ± 2 21 ± 3 20 ± 3 19 ± 3
Cells/mm3 809 ± 459 933 ± 510 692 ± 326 909 ± 451 684 ± 286
CD8 % 51 ± 8 53 ± 10 53 ± 9 58 ± 11 55 ± 11
Cells/mm3 1885 ± 883 2341 ± 1411 1757 ± 853 2488 ± 738 2008 ± 1048
VL (Log10) copies/ml 5.0 -- 4.63 -- 4.6
IC3 N a (Nd) 4(9) 4(4) 4(4) 4(4) 4(4)
DC % 0.40 ± 0.14 0.37 ± 0.06 0.42 ± 0.39 0.47 ± 0.12 0.57 ± 0.10
Cells/mm3 33 ± 18 26 ± 12 51 ± 35 36 ± 10 51 ± 22
mDC % 0.28 ± 0.09 0.26 ± 0.06 0.28 ± 0.26 0.33 ± 0.13 0.40 ± 0.08
Cells/mm3 23 ± 12 18 ± 9 31 ± 27 26 ± 10 36 ± 15
pDC % 0.12 ± 0.07 0.11 ± 0.04 0.14 ± 0.10 0.14 ± 0.03 0.16 ± 0.03
Cells/mm3 10 ± 7 8 ± 5 19.89 ± 8.13 11 ± 3 15 ± 7
CD3 % 81 ± 14 77 ± 20 87 ± 6 84 ± 6 79 ± 10
Cells/mm3 2780 ± 1864 2424 ± 1413 4691 ± 1652 2492 ± 435 2329 ± 1022
CD4 % 9 ± 3 12 ± 2 13 ± 2 12 ± 2 11 ± 3
Cells/mm3 275 ± 132 357 ± 177 670 ± 158 376 ± 118 348 ± 185
CD8 % 66 ± 14 60 ± 18 68 ± 8 67 ± 8 63 ± 12
Cells/mm3 2286 ± 1661 1923 ± 1190 3766 ± 1663 1988 ± 341 1846 ± 805
VL (Log10) copies/ml 5.24 -- 5.48 -- 5.23
HAART N a (Nd) 8b(9) 8(9) 8(9) 8(9) 8(8)
DC % 0.42 ± 0.25 0.28 ± 0.15 0.44 ± 0.17 0.40 ± 0.08 0.34 ± 0.04
Cells/mm3 33 ± 28 27 ± 18 36 ± 22 32 ± 3 27 ± 6
mDC % 0.31 ± 0.17 0.21 ± 0.08 0.31 ± 0.13 0.31 ± 0.02 0.24 ± 0.03
Cells/mm3 25 ± 19 20 ± 11 27 ± 19 26 ± 7 19 ± 4
pDC % 0.11 ± 0.08 0.07 ± 0.08 0.13 ± 0.05 0.09 ± 0.07 0.1 ± 0.05
Cells/mm3 9 ± 9 7 ± 7 9 ± 4 6 ± 4 8 ± 3
CD3 % 75 ± 14 83 ± 4 81 ± 8 83 ± 4 80 ± 3
Cells/mm3 2969 ± 1808 3103 ± 994 3190 ± 1185 3122 ± 1160 2686 ± 545
CD4 % 13 ± 2 25 ± 2 24 ± 6 34 ± 7 30 ± 3
Cells/mm3 477 ± 156 906 ± 185 1059 ± 351 1303 ± 489 942 ± 99
CD8 % 55 ± 16 53 ± 7 53 ± 8 45 ± 10 44 ± 3
Cells/mm3 2243 ± 1596 1991 ± 740 1963 ± 888 1681 ± 978 1564 ± 408
cVL (Log10) copies/ml 5.5 -- 3.25 -- 3.01
a

N - Number of samples taken for analysis;

d

N - Total number of samples collected

b

-Before Initiation of HAART ; Data are Mean ± SD

c

– VL - Viral Load; Data are Median