Fig. 8.
Relationship between ERK pathway and [Ca2+]i. A Observation the effect of ERK pathway on Ca2+ level by fluorescence microscopy. a HepG2 cells were incubated with surfactin (42 μg/ml) for 0 h. b HepG2 cells were incubated with surfactin (42 μg/ml) for 9 h. c HepG2 cells were incubated with 10 μM PD98059 for 9 h. d 10 μM PD98059 was added into HepG2 cells for 2 h, then incubated with surfactin (42 μg/ml) for 9 h. B Testing the impact of the Ca2+ level in MAPK pathways by western blotting. C Quantification of effect of BAPTA on P-ERK expression in HepG2 cells. **p < 0.01 compared with surfactin group