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. 2013 May 14;24(12):2049–2057. doi: 10.1007/s00192-013-2112-0

Table 2.

Statistics for gene expression (RT-qPCR)

Variable Descriptive statistics BPS/IC ESSIC type 3Ca (group 1, n = 15) OABa (group 2, n = 11) Healthy controlsa (group 3, n = 8) p value Post hoc test Bonferroni correction (p < 0.016)
CD79A_qPCR Mean 11.16 0.36 0.29 p < 0.0001 Gr. 1&2 (p < 0.0001) S
σb 9.17 0.56 0.47 Gr. 1&3 (p < 0.0001) S
Median 8.94 0.12 0.06 Gr. 2&3 (p = 0.215) NS
Minimum 1.30 0.02 0.01
Maximum 40.90 1.96 1.22
CD20_qPCR Mean 14.11 0.71 0.21 p < 0.0001 Gr. 1&2 (p < 0.0001) S
σb 9.71 1.72 0.46 Gr. 1&3 (p < 0.0001) S
Median 13.58 0.16 0.01 Gr. 2&3 (p = 0.240) NS
Minimum 1.50 0.00 0.00
Maximum 33.78 5.85 1.31
CTLA4_qPCR Mean 13.62 0.78 0.53 p < 0.0001 Gr. 1&2 (p < 0.0001) S
σb 10.77 0.55 0.51 Gr. 1&3 (p < 0.0001) S
Median 10.13 0.57 0.25 Gr. 2&3 (p = 0.107) NS
Minimum 2.39 0.28 0.14
Maximum 35.67 1.95 1.55
IGH@_qPCR Mean 44.11 0.75 1.01 p < 0.0001 Gr. 1&2 (p < 0.0001) S
σb 53.58 0.91 1.83 Gr. 1&3 (p < 0.0001) S
Median 23.71 0.33 0.22 Gr. 2&3 (p = 0.563) NS
Minimum 1.30 0.01 0.00
Maximum 158.19 2.79 5.28
KRT20_qPCR Mean 0.22 1.84 2.31 p < 0.0001 Gr. 1&2 (p < 0.0001) S
σb 0.63 1.97 1.69 Gr. 1&3 (p < 0.0001) S
Median 0.00 1.02 2.13 Gr. 2&3 (p = 0.283) NS
Minimum 0.00 0.22 0.27
Maximum 2.32 6.69 5.78
UPK1B_qPCR Mean 0.13 0.87 1.37 p < 0.0001 Gr. 1&2 (p < 0.0001) S
σb 0.18 0.41 0.32 Gr. 1&3 (p < 0.0001) S
Median 0.03 0.69 1.44 Gr. 2&3(p = 0.013) S
Minimum 0.00 0.27 0.80
Maximum 0.65 1.52 1.78
UPK3A_qPCR Mean 0.13 1.02 1.97 p < 0.0001 Gr. 1&2 (p < 0.0001) S
σb 0.30 0.64 0.81 Gr. 1&3 (p < 0.0001) S
Median 0.03 1.02 2.13 Gr. 2&3 (p = 0.021) NS
Minimum 0.00 0.28 0.73
Maximum 1.13 2.50 3.27

Gr. group, S significant, NS not significant

aRelative gene expression

bσ: standard deviation