Table 2.
Variable | Descriptive statistics | BPS/IC ESSIC type 3Ca (group 1, n = 15) | OABa (group 2, n = 11) | Healthy controlsa (group 3, n = 8) | p value | Post hoc test | Bonferroni correction (p < 0.016) |
---|---|---|---|---|---|---|---|
CD79A_qPCR | Mean | 11.16 | 0.36 | 0.29 | p < 0.0001 | Gr. 1&2 (p < 0.0001) | S |
σb | 9.17 | 0.56 | 0.47 | Gr. 1&3 (p < 0.0001) | S | ||
Median | 8.94 | 0.12 | 0.06 | Gr. 2&3 (p = 0.215) | NS | ||
Minimum | 1.30 | 0.02 | 0.01 | ||||
Maximum | 40.90 | 1.96 | 1.22 | ||||
CD20_qPCR | Mean | 14.11 | 0.71 | 0.21 | p < 0.0001 | Gr. 1&2 (p < 0.0001) | S |
σb | 9.71 | 1.72 | 0.46 | Gr. 1&3 (p < 0.0001) | S | ||
Median | 13.58 | 0.16 | 0.01 | Gr. 2&3 (p = 0.240) | NS | ||
Minimum | 1.50 | 0.00 | 0.00 | ||||
Maximum | 33.78 | 5.85 | 1.31 | ||||
CTLA4_qPCR | Mean | 13.62 | 0.78 | 0.53 | p < 0.0001 | Gr. 1&2 (p < 0.0001) | S |
σb | 10.77 | 0.55 | 0.51 | Gr. 1&3 (p < 0.0001) | S | ||
Median | 10.13 | 0.57 | 0.25 | Gr. 2&3 (p = 0.107) | NS | ||
Minimum | 2.39 | 0.28 | 0.14 | ||||
Maximum | 35.67 | 1.95 | 1.55 | ||||
IGH@_qPCR | Mean | 44.11 | 0.75 | 1.01 | p < 0.0001 | Gr. 1&2 (p < 0.0001) | S |
σb | 53.58 | 0.91 | 1.83 | Gr. 1&3 (p < 0.0001) | S | ||
Median | 23.71 | 0.33 | 0.22 | Gr. 2&3 (p = 0.563) | NS | ||
Minimum | 1.30 | 0.01 | 0.00 | ||||
Maximum | 158.19 | 2.79 | 5.28 | ||||
KRT20_qPCR | Mean | 0.22 | 1.84 | 2.31 | p < 0.0001 | Gr. 1&2 (p < 0.0001) | S |
σb | 0.63 | 1.97 | 1.69 | Gr. 1&3 (p < 0.0001) | S | ||
Median | 0.00 | 1.02 | 2.13 | Gr. 2&3 (p = 0.283) | NS | ||
Minimum | 0.00 | 0.22 | 0.27 | ||||
Maximum | 2.32 | 6.69 | 5.78 | ||||
UPK1B_qPCR | Mean | 0.13 | 0.87 | 1.37 | p < 0.0001 | Gr. 1&2 (p < 0.0001) | S |
σb | 0.18 | 0.41 | 0.32 | Gr. 1&3 (p < 0.0001) | S | ||
Median | 0.03 | 0.69 | 1.44 | Gr. 2&3(p = 0.013) | S | ||
Minimum | 0.00 | 0.27 | 0.80 | ||||
Maximum | 0.65 | 1.52 | 1.78 | ||||
UPK3A_qPCR | Mean | 0.13 | 1.02 | 1.97 | p < 0.0001 | Gr. 1&2 (p < 0.0001) | S |
σb | 0.30 | 0.64 | 0.81 | Gr. 1&3 (p < 0.0001) | S | ||
Median | 0.03 | 1.02 | 2.13 | Gr. 2&3 (p = 0.021) | NS | ||
Minimum | 0.00 | 0.28 | 0.73 | ||||
Maximum | 1.13 | 2.50 | 3.27 |
Gr. group, S significant, NS not significant
aRelative gene expression
bσ: standard deviation