Fig. 5.

Inflammation marker in Raw 264.7-treated cells. Cells were incubated with (0/5/10/20/40 μM) lovastatin for 20 h alone or with the addition of 10 μg/mL LPS for supplementary 24 h. Bars represent the mean values of NO (in micromolars), IL-1β, IL-6 and IL-12p40 (pg/ml) of three independent experiments ± SD. Analyses were performed with one-way ANOVA and Bonferroni post-test. *p < 0.05; **p < 0.01; ***p < 0.001 vs. 0 μM Lova (white bars); §p < 0.05; §§p < 0.01; §§§p < 0.001 vs. LPS + 0 μM Lova (grey bars)