Table 2.
Incidence rate (CPM) and percentage of clinical cases for each disease
| Incidence rate (CPM) | ||||||||
| Facility A | Facility B | Facility C | Facility D | Overall | 95% confidence interval | % of clinical cases | ||
| Nonspecific systemic diseases | Spontaneous mortality with unknown cause—adults | 30.21 ± 0.48 (27.66–33.71) | 16.01 ± 1.14 (10.20–23.13) | 28.15 ± 1.01 (22.17–35.49) | 33.50 ± 1.37 (25.10–41.25) | 27.13 ± 0.54 (24.18–31.68) | 25.95–28.31 | |
| Spontaneous mortality with unknown cause—pups | 39.88 ± 2.82 (21.54–51.39) | 2.21 ± 0.56 (0.34–7.33) | 1.80 ± 0.28 (0.12–3.42) | 18.83 ± 2.95 (3.17–36.43) | 17.72 ± 1.08 (11.43–23.96) | 15.36–20.08 | ||
| Lethargy, poor haircoat, etc | 1.49 ± 0.24 (0.80–4.38) | 0.32 ± 0.10 (0.00–1.27) | 0.99 ± 0.15 (0.13–1.83) | 3.63 ± 0.33 (1.86–6.11) | 1.49 ± 0.13 (1.01–2.76) | 1.21–1.77 | 11.0 | |
| Muscle wasting | 0.73 ± 0.11 (0.22–1.46) | 0.16 ± 0.05 (0.00–0.65) | 0.78 ± 0.11 (0.13–1.60) | 1.94 ± 0.32 (0.58–4.69) | 0.79 ± 0.08 (0.36–1.28) | 0.61–0.97 | 5.6 | |
| Moribund | 0.24 ± 0.03 (0.10–0.44) | 0.18–0.30 | 1.8 | |||||
| Dermatitis | All anatomic locations | 2.51 ± 0.17 (1.43–3.33) | 1.75 ± 0.17 (0.51–2.98) | 1.97 ± 0.19 (0.57–3.20) | 9.08 ± 0.67 (5.66–12.97) | 3.11 ± 0.12 (2.57–4.02) | 2.85–3.37 | 21.7 |
| Ulcerative dermatitis and dermatitis of dorsal neck and pinnas | 1.42 ± 0.13 (0.55–2.12) | 1.14 ± 0.14 (0.51–2.10) | 0.85 ± 0.13 (0.23–1.59) | 4.69 ± 0.60 (1.62–8.83) | 1.65 ± 0.09 (1.17–2.30) | 1.46–1.84 | ||
| Face, muzzle, and nose | 0.51 ± 0.07 (0.18–0.84) | 0.20 ± 0.05 (0.00–0.67) | 0.29 ± 0.07 (0.00–0.68) | 1.57 ± 0.24 (0.58–3.42) | 0.52 ± 0.04 (0.30–0.84) | 0.44–0.60 | ||
| Back and flanks | 0.21 ± 0.07 (0.00–0.83) | 0.15 ± 0.06 (0.00–0.53) | 0.30 ± 0.06 (0.11–0.77) | 1.24 ± 020 (0.00–2.20) | 0.37 ± 0.03 (0.17–0.54) | 0.30–0.44 | ||
| Hindlimbs | 0.17 ± 0.02 (0.00–0.26) | 0.13–0.21 | ||||||
| Ventral neck | 0.12 ± 0.02 (0.00–0.20) | 0.08–0.16 | ||||||
| Base of tail and tail | 0.11 ± 0.02 (0.00–0.26) | 0.05–0.17 | ||||||
| Fight wounds | Fight wounds | 2.21 ± 0.06 (1.66–2.50) | 1.23 ± 0.14 (0.17–2.12) | 1.30 ± 0.16 (0.34–2.39) | 4.81 ± 0.54 (1.56–8.28) | 2.10 ± 0.06 (1.66–2.50) | 1.97–2.23 | 14.7 |
| Ocular lesions | Eye | 0.73 ± 0.13 (0.10–1.85) | 0.31 ± 0.07 (0.00–0.56) | 0.99 ± 0.27 (0.11–3.20) | 4.73 ± 0.13 (1.01–2.76) | 1.28 ± 0.13 (0.67–2.04) | 1.00–1.56 | 8.9 |
| Female reproductive and neonatal diseases | Dystocia | 0.81 ± 0.08 (0.30–1.50) | 0.04 ± 0.03 (0.00–0.57) | 0.19 ± 0.05 (0.00–0.57) | 0.57 ± 0.09 (0.00–1.39) | 0.43 ± 0.04 (0.24–0.68) | 0.35–0.51 | 3.0 |
| Neonates with clinical disease | 0.86 ± 0.08 (0.30–1.29) | 0.11 ± 0.04 (0.00–0.35) | 0.13 ± 0.03 (0.00–0.34) | 0.76 ± 0.12 (0.23–1.72) | 0.48 ± 0.02 (0.34–0.62) | 0.43–0.53 | 3.3 | |
| Prolapsed vagina or uterus | 0.14 ± 0.03 (0.03–0.40) | 0.08–0.20 | 1.0 | |||||
| Tumors | Tumors | 0.72 ± 0.10 (0.19–1.54) | 0.34 ± 0.07 (0.00–0.69) | 0.63 ± 0.14 (0.13–1.94) | 3.08 ± 0.48 (1.08–6.35) | 0.94 ± 0.08 (0.47–1.45) | 0.76–1.12 | 6.5 |
| Malocclusion | Malocclusion | 0.35 ± 0.05 (0.09–0.64) | 0.14 ± 0.04 (0.00–0.42) | 1.19 ± 0.19 (0.46–3.31) | 0.98 ± 0.17 (0.00–1.95) | 0.65 ± 0.06 (0.44–1.24) | 0.53–0.77 | 4.5 |
| Prolapsed rectum | Prolapsed rectum | 0.70 ± 0.06 (0.27–1.02) | 0.17 ± 0.06 (0.00–0.73) | 0.36 ± 0.06 (0.11–0.84) | 1.03 ± 0.15 (0.00–1.72) | 0.54 ± 0.04 (0.34–0.83) | 0.46–0.62 | 3.7 |
| Iatrogenic disease | Watering failures | 0.23 ± 0.03 (0.03–0.44) | 0.16–0.30 | 1.7 | ||||
| Iatrogenic lameness | 0.07 | 0.5 | ||||||
| Neurologic disease | Head tilt | 0.29 ± 0.04 (0.00–0.57) | 0.20–0.38 | 2.1 | ||||
| Paresis, paralysis | 0.18 ± 0.02 (0.03–0.27) | 0.14–0.22 | 1.3 | |||||
| Hydrocephalus | 0.17 ± 0.03 (0.03–0.40) | 0.11–0.23 | 1.2 | |||||
| Ataxia | 0.05 | <1 | ||||||
| Male urogenital diseases | Prolapsed penis | 0.20 ± 0.03 (0.03–0.36) | 0.13–0.27 | 1.5 | ||||
| Preputial gland disease | 0.12 ± 0.02 (0.00–0.30) | 0.07–0.17 | <1 | |||||
| Miscellaneous | Secondary Enterobacter infections in immunosuppressed mice | 0.28 ± 0.10 (0.00–1.11) | 0.07–0.49 | 2.0 | ||||
| Distended abdomen, ascites | 0.15 ± 0.02 (0.04–0.37) | 0.10–0.20 | 1.1 | |||||
| Lame | 0.14 ± 0.04 (0.00–0.27) | 0.05–0.23 | 1.1 | |||||
| Abscesses (not involving the preputial gland) | 0.07 | <1 | ||||||
| Perineal hernia or scrotal disease | 0.06 | <1 | ||||||
| Respiratory disease | 0.05 | <1 | ||||||
Data are presented as mean ± SE (range). Diseases reported more than 120 times were analyzed by both facility and month. Diseases reported between 40 and 120 times were analyzed by month, with all of the facilities pooled. Diseases reported fewer than 40 times were analyzed as cases during the year by total number of cages in all 4 facilities.