Table 1.
Dose cohort (mg) | Patient number | Start time of response (h) | Duration of response (h) |
---|---|---|---|
100 | 104 | 1.0 | 6.9 |
400 | 109a | 2.0 | 4.5 |
303 | 1.2 | 22.9 | |
500 | 112 | 1.0 | 23.0 |
304 | 1.3 | 6.9 | |
306 | 4.1 | 20.1 | |
401 | 1.1 | 4.1 |
Positive response was either complete suppression or partial response.
Patient met both complete and partial suppression criteria. The temporal variables were calculated based on the first and last time point of positive response, and longest duration.