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The annexin A2 hetero-tetramer (AIIt) stimulates increases in cell number via binding to TLR4. (A) Cell number following incubation with AIIt (200 ng·mL−1) and/or plasmin (Plm, 5 mU·mL−1) for 48 h. (B) Cell number following incubation with AIIt (200 ng·mL−1) or LPS (10 ng·mL−1), with or without anti-TLR4 IgG (1 μg·mL−1) for 48 h. *P < 0.05 (n = 3–5).
