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. 2013 Nov 19;105(10):2392–2402. doi: 10.1016/j.bpj.2013.09.048

Figure 7.

Figure 7

Mechanism of unfolding of barstar. The kinetic scheme of unfolding is shown, along with the probes used to interrogate the individual steps and the rates that these probes yield. The mechanism shown is a minimal mechanism and describes the sequence of structural events that occur during unfolding. It does not preclude more complex schemes that invoke multiple pathways or a continuum of intermediates.