DNMT1, DNMT3a and DNMT3b mRNA expression in the developing rat brain. Columns show autoradiograms from representative tissue sections through the developmental rat brain at postnatal day (P)1, P4, P7, P10, P14, and P21 that were processed by in situ hybridization with antisense probe against rat DNMT1 (top column), DNMT3a (middle column) and DNMT3b (bottom column) mRNA. X-ray films were exposed for 8 days for DNMT1, 3 days for DNMT3a, and 17 days for DNMT3b.