Developmental patterns of DNMT1, DNMT3a and DNMT3b mRNA expression in the early rodent postnatal period and adulthood. DNA methyltransferase (DNMT)1, DNMT3a, and DNMT3b mRNA expression levels were quantified in several regions of rat brains collected at 6 developmental timepoints – postnatal day (P)1, P4, P7, P10, P14, P21, and P75 (adulthood). (A) Developmental expression pattern of DNMT1, DNMT3a, and DNTM3b in subregions of the hippocampus (CA1–3 and dentate gyrus). (B) Developmental expression pattern of DNMT1, DNMT3a, and DNMT3b in subnuclei of the amygdala (lateral, basolateral, medial and central nucleus). (C) Developmental expression pattern of DNMT1 and DNMT3a in several forebrain regions, including cingulate (Cg) and lateral septum (LS). Due to low abundance, DNMT3b was unable to be quantified in these regions. (D) Developmental expression pattern of DNMT1 and DNMT3a in the striatum (caudate putamen (Cpu) and nucleus accumbens (Acb)). Due to low abundance, DNMT3b was unable to be quantified in these regions.