Skip to main content
. Author manuscript; available in PMC: 2013 Nov 25.
Published in final edited form as: Cereb Cortex. 2003 Feb;13(2):144–154. doi: 10.1093/cercor/13.2.144

Table 2.

Typical adaptation dynamics: brain regions demonstrating significant load response and practice effects in the object-location learning task following placebo treatment (n = 24)

Region (approx. Brodmann area) Talairach coordinates of 2-D cluster centroid (mm)
Cluster area
(voxels)
x y z
(A) Main locations of load response (increased signal with increased load)
Insula 32 8 −12 15
34 6 −8 11
32 −6 −8 16
Parahippocampal gyrus 20 −31 −8 11
(BA 28, 35) 22 −30 −4 103
Anterior cingulate gyrus −5 41 −4 28
(BA 24, 32) −11 41 1 32
−11 40 4 33
−9 37 8 58
−5 40 12 48
−6 39 16 118
10 37 20 107
16 32 24 140
18 31 28 117
8 19 32 277
Inferior/middle frontal gyrus 30 0 20 150
(BA 44, 46) −38 21 20 21
Caudate nucleus 18 17 4 48
17 17 8 45
Putamen 28 −14 12 56
(B) Main locations of practice effects (habituation of signal as a linear function of between-block repetition)
Cerebellum 21 −58 −28 188
21 −56 −24 176
−6 −53 −20 130
Fusiform gyrus 31 −38 −16 33
(BA 19, 20) 43 −67 −12 50
Lingual gyrus −18 −87 −12 36
(BA 18, 19) −29 −55 −4 106
Inferior temporal gyrus 45 −67 −8 51
(BA 37)
Parahippocampal gyrus −18 −52 1 46
3 −35 4 7
Thalamus −10 −10 8 92
Anterior cingulate gyrus −15 15 24 41
(BA 24, 32) −14 17 28 78
−11 15 32 80
Superior occipital gyrus 26 80 24 59
(BA 19) 29 −69 28 37
28 −67 32 30
Inferior parietal lobule 34 −67 40 39
(BA 7, 40) 31 −70 45 45