Table 2.
Distribution of the karyotypes of 128 B-precursor acute lymphoblastic leukemia patients
| Group | Frequency/% | Children | Adult | P value |
|---|---|---|---|---|
| Normal | 49/38.3% | 33/37.5% | 16/40% | 0.94 |
| Pseudodiploidy | 10/7.8% | 10/11.4% | 0 | 0.41 |
| Hyperdiploidy (47-50): | 0.96 | |||
| A) pure | 5/3.9% | 4/4.5% | 1/2.5% | |
| B) other abnormalities | 1/0.8% | 0 | 1/2.5% | |
| Hyperdiploidy (51-65): | ||||
| A) pure | 25/19.5% | 24/27.3% | 1/2.5% | 0.0024 |
| B) other abnormalities | 6/4.7% | 4/4.5% | 2/5% | 0.74 |
| Hyperdiploidy (>65): | 0.36 | |||
| A) pure | 5/3.5% | 2/2.3% | 3/7.5% | |
| B) other abnormalities | 0 | 0 | 0 | |
| Hypodiploidy: | 0.78 | |||
| A) pure | 1/0.8% | 1/0.8% | 0 | |
| B) other abnormalities | 4/3.1% | 3/3.4% | 1/2.5% | |
| Translocation (9;22): | ||||
| A) pure | 8/6.3% | 1/1.1% | 7/17.5% | 0.0009 |
| B) other abnormalities | 6/4.7% | 1/1.1% | 5/12.5% | 0.0017 |
| -7/7q deletion | 3/2.3% | 2/2.3% | 1/2.5% | 0.57 |
| 11q23 | 2/1.5% | 1/1.1% | 1/2.5% | |
| Translocation (1;19) | 2/1.5% | 1/1.1% | 1/2.5% | |
| 6q deletion | 1/0.8% | 1/1.1% | 0 | |
| Total | 128/100% | 88/100% | 40/100% |