Table 1.
Demographical and anatomical information of the sample.
| AD | aMCI | CTR | |
|---|---|---|---|
| N | 40 | 20 | 25 |
| Age [years, mean (SD)] | 73.7 (12) | 73.9 (5.4) | 70.2 (5.1) |
| Sex (M:F) | 17:23 | 12:8 | 11:14. |
| MMSE score [mean (SD)] | 20.2 (2.7) (§) | 25.6 (1.7) (∧) | 29.1 (0.7) (#) |
| CDR (range) | 1–1.5 (§) | 0–0.5 | 0 |
| Right hippocampal volume [mm3, mean (SD)] | 2898 (575) (§) | 3158 (519) (∧) | 3774 (558) (#) |
| Left hippocampal volume [mm3, mean (SD)] | 2719 (482) (§) | 3065 (489) (∧) | 3607 (450) (#) |
AD, Alzheimer’s disease; aMCI, amnestic mild cognitive impairment; CTR, healthy controls; MMSE, mini-mental state evaluation; CDR, clinical dementia rating scale; SD, standard deviation. Chi-squared test was used for gender comparison and one-way ANOVA with Bonferroni post hoc test was used for age, MMSE score and hippocampal volumes comparisons (significance level: p < 0.05). (#) Significant compared to MCI and AD group; (§) significant compared to MCI and CTR; (∧) significant compared to AD and CTR.