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. Author manuscript; available in PMC: 2014 Oct 21.
Published in final edited form as: Chem Res Toxicol. 2013 Oct 8;26(10):10.1021/tx400293s. doi: 10.1021/tx400293s

Figure 4. Uptake and cytotoxicity of Cr(VI) in FANCD2-null and FANCD2-complemented human fibroblasts.

Figure 4

Data are meansĀ±SD (n=3-6). Cells were preincubated with the indicated concentrations of DHA for 90 min prior to the addition of Cr(VI). All treatments with Cr(VI) were 6-hr long. (A) Cellular concentrations of Asc after preincubation with DHA. (B) Cr(VI) uptake by cells preincubated with 0.5 and 1 mM DHA. (C) Cell viability at 72 hr after exposure to Cr(VI). (D) Growth inhibition by Cr(VI). (E) Clonogenic survival of Cr(VI)-treated cells.