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. Author manuscript; available in PMC: 2014 Oct 21.
Published in final edited form as: Chem Res Toxicol. 2013 Oct 8;26(10):10.1021/tx400293s. doi: 10.1021/tx400293s

Figure 6. Cytotoxicity of Cr(VI) in cells with shRNA-depleted XPF-ERCC1 endonuclease.

Figure 6

(A) Western blots demonstrating XPF and ERCC1 knockdowns in XPA-null human fibroblasts. (B) Cytotoxicity of Cr(VI) in control (shSCR) and XPF/ERCC1-depleted (shXPF/shERCC1) cells. Cells were preloaded with 2.5 mM Asc prior to 6-hr long treatment with Cr(VI) and cell viability was measured at 72 hr post-exposure. Data are means±SD (n=6).