Skip to main content
. Author manuscript; available in PMC: 2014 Nov 27.
Published in final edited form as: Transplantation. 2013 Nov 27;96(10):10.1097/TP.0b013e3182a4190e. doi: 10.1097/TP.0b013e3182a4190e

Figure 1. Entry of SNA-NC into islet cells and knockdown of IKKβ by IKKβ SNA-NCs.

Figure 1

A. Schematic of IKKβ SNA-NC uptake by host cell and target protein regulation. Inset: Representation of a siRNA-functionalized SNA-NC. B. RT-qPCR results of IKKβ knockdown in isolated mouse islets treated with either 10 nM IKKβ SNA-NC or 10 nM SCR SNA-NC for 24 hours, then cultured for an additional 0, 24, 48, 72 or 96 hours. *p<0.05 when compared to untreated control at t=0. **p<0.01 when compared to untreated control at t=0.