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. Author manuscript; available in PMC: 2014 Nov 27.
Published in final edited form as: Transplantation. 2013 Nov 27;96(10):10.1097/TP.0b013e3182a4190e. doi: 10.1097/TP.0b013e3182a4190e

Figure 3. Effect of IKKβ SNA-NC treatment islet cell viability and β cell mass in vitro.

Figure 3

A. Flow cytometric analysis of viability of islets treated with 10 nM IKKβ SNA-NC or 10 nM SCR SNA-NC for 24 hours prior to 24 hour CM exposure. Data presented as percent viable cells. B. Flow cytometric analysis of β cell percentage of islets treated with10 nM IKKβ SNA-NC or 10 nM SCR SNA-NC for 24 hours prior to 24 hour CM exposure. Data are presented as percent of total cell population. C. Tg(PRIP-luc) islets treated with 10 nM IKKβ SNA-NC or 10 nM SCR SNA-NC for 24 hours prior to 48 hour CM exposure. Data are presented as percentage of luminescent signal at time 0 of CM exposure. CM= 50 U/mL IL-1β, 1000 U/mL TNF-α, 750 U/mL IFN-γ. *p<0.05