Figure 5. Presence of CD11b+ cells in intra-portally transplanted islet grafts over time.

Isolated mouse islets were treated with 10 nM IKKβ SNA-NC, 10 nM SCR SNA-NC, or untreated for 24 hours prior to intra-portal transplantation to STZ-induced diabetic recipients. A minimum of 200 islets were transplanted per recipient. Livers were harvested on days 3, 7 and 30, fixed with 4% paraformaldehyde, sectioned and stained for insulin (green), CD11b (red) and DAPI (blue). Images were taken under 20× magnification.