Table 3.

Voxel-wise correlations with depression severity (CDRS-R).

Region	Tract	COG			Cluster size
		x	y	z
FA: POSITIVE RELATIONSHIP
None
FA: NEGATIVE RELATIONSHIP
L cerebral WM (PHG)	Sagittal stratum (ILF + IFOF)	−42	−35	−9	29
L cerebral WM (pallidum)	ATR	−10	−3	−3	20
L cerebral WM (ACC)	Genu of corpus callosum	−2	30	4	14
L cerebral WM (precuneus)	Anterior cingulum	−7	−72	39	11
MD: POSITIVE RELATIONSHIP
L cerebral WM (PHG)	Sagittal stratum (ILF + IFOF)	−41	−33	−13	20
R cerebral WM (pallidum)	ATR	14	−3	3	11
R cerebral WM (postcentral gyrus)	Corticospinal	22	−40	47	10
MD: NEGATIVE RELATIONSHIP
None
RD: POSITIVE RELATIONSHIP
L cerebral WM (PHG)	Sagittal stratum (ILF + IFOF)	−42	−35	−10	45
L cerebral WM (pallidum)	ATR	−10	−3	−4	17
R cerebral WM (supramarginal gyrus)	SLF	30	−39	37	13
L cerebral WM (ACC)	Genu of corpus callosum	−2	29	4	14
R cerebral WM (pallidum)	ATR	14	−2	3	10
RD: NEGATIVE RELATIONSHIP
None
AD: POSITIVE RELATIONSHIP
R cerebral WM (postcentral gyrus)	Corticospinal	22	−33	44	25
R cerebral WM (precuneus)	IFOF	23	−55	30	17
L cerebral WM (MFG)	SLF	−31	21	25	10
R cerebral WM (OFC)	Frontal projection fibers	−24	19	−18	10
AD: NEGATIVE RELATIONSHIP
None

Coordinates in MNI space. Threshold p < 0.001, uncorrected, k > 10. COG, center of gravity; L, left; R, right; FA, fractional anisotropy; MD, mean diffusivity; RD, radial diffusivity; AD, axial diffusivity; WM, white matter; PHG, parahippocampal gyrus; ACC, anterior cingulate cortex; MFG, medial frontal gyrus; OFC, orbitofrontal gyrus; ILF; inferior longitudinal fasciculus; IFOF, inferior-fronto-occipital fasciculus; ATR, anterior thalamic radiation; SLF, superior longitudinal fasciculus.