Fig. 4.

Candidate genes interact genetically with nmo and could have a role in ommatidial rotation. (A–F) Tangential sections of adult eyes of the indicated genotypes and the corresponding schematic representations of ommatidial orientation with respect to equator, with dorsal and ventral chiral forms indicated by black and red arrows, respectively. Circles represent ommatidia with incorrect number of PRs and the green arrow indicates a symmetric ommatidium. Experiments were performed at 29 °C in (A), (D) and (E) and at 25 °C in (B), (C) and (F). (G) Quantification of the percentage of wild type ommatidia and ommatidia with rotation defects in adult eyes of the indicated genotypes. Note that in all cases, there is a significant modification of the sev > nmo phenotype (*p-value<0.05, **p-value<0.01, Student's t-test).