Table 2. On-treatment medications and risk factor control of overall patients.
Caucasians (n=3,309) | African-Americans (n=170) | P-value | |
---|---|---|---|
Concomitant medications | |||
Statin use (%) | 94.7 | 92.9 | 0.33 |
Beta-blocker use (%) | 76.4 | 78.8 | 0.46 |
Aspirin use (%) | 94.5 | 88.8 | 0.002 |
ACE inhibitor use (%) | 55.1 | 52.4 | 0.48 |
Calcium-channel blocker use (%) | 37.7 | 48.2 | 0.006 |
Oral anti-diabetic drug (%) | 28.0 | 43.5 | <0.001 |
Insulin (%) | 9.3 | 19.4 | <0.001 |
On-treatment parameters | |||
Total cholesterol (mmol/L) (mean ± SD) | 4.2±0.9 | 4.4±0.9 | 0.06 |
LDL-cholesterol (mmol/L) (mean ± SD) | 2.2±0.7 | 2.4±0.7 | 0.006 |
HDL-cholesterol (mmol/L) (mean ± SD) | 1.2±0.4 | 1.3±0.4 | 0.001 |
Triglyceride (mmol/L) [median (interquartile range)] | 1.5 (1.1, 2.0) | 1.2 (0.9, 1.6) | <0.001 |
Non-HDL cholesterol (mmol/L) | 2.9±1.0 | 2.9±1.1 | 0.75 |
CRP (mg/dL) [median (interquartile range)] | 2.0 (1.0, 4.4) | 2.9 (1.3, 7.0) | <0.001 |
HbA1c (%) (mean ± SD) | 6.4±1.2 | 7.3±1.7 | <0.001 |
Fasting glucose (mmol/L) (mean ± SD) | 6.4±1.9 | 6.7±2.3 | 0.17 |
Systolic blood pressure (mmHg) (mean ± SD) | 128±13 | 133±15 | <0.001 |
Diastolic blood pressure (mmHg) (mean ± SD) | 76±7 | 78±7 | 0.001 |
The prevalence of patients with optimal controlled risk | |||
LDL-C < 2.1 mmol/L (%) | 42.8 | 34.1 | 0.02 |
CRP < 2.0 mg/dL (%) | 49.3 | 37.3 | 0.004 |
Systolic blood pressure <130 mmHg (%) | 58.9 | 44.2 | <0.001 |
ACE, angiotensine converting enzyme; CRP, c-reactive protein; HbA1c, glycated hemoglobin; HDL, high-density lipoprotein; LDL, low-density lipoprotein