Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2013 Nov 25;4:403. doi: 10.3389/fimmu.2013.00403

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2013 van de Ven, Lindenberg, Oosterhoff and de Gruijl.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Interference by tumor-associated soluble factors with normal dendritic cell (DC) development through indicated underlying signaling pathways, leads to (trans-)differentiation of CD14⁺ M2-macrophage-like cells with immune-suppressive and tumor growth- and invasion-promoting properties. Photographic inserts illustrate the DC and adherent macrophage-like morphology of human skin-emigrated CD83⁺ and CD14⁺ DC, respectively (magnification 400×). Abbreviations: IL, interleukin; PGE2, prostaglandin-E2.