Antitumor effects of AF and AJ. Mice bilaterally implanted with MDA-MB-231 breast cancer cells were treated with 2.0 mg/kg of AF on days 1, 4 and 8, 2.5 mg/kg AF on days 1 and 5 or 0.5 mg/k AJ on days 1, 3, 5 and 8. PTX was administered at a dose of 10 mg/kg on days 1, 3, 5 and 8 as a positive control. Median tumor volumes with standard error of the mean (n = 10) are graphically represented. **p < 0.01.