Table1.
The correlation of SIRT1 expression levels with Gleason score of prostate cancer tissues. The tissue arrays containing 65 cancer, 6 normal, and 24 BPH prostate tissues from Cybrdi (CC19-11-007; CC-19-005 and CC19-01) were examined via standard IHC methods (DAB kit, DAB150, Upstate) using SIRT1 antibody (1:2000, Upstate). The correlations between SIRT1 expression and tumor Gleason score were evaluated by Fisher’s exact test (p<0.01).
| Tissue Type | Tissue Number | SIRT1 level | ||
|---|---|---|---|---|
| Low N (%) |
Medium N (%) |
High N (%) |
||
| Normal | 6 | 4 (66.6%) | 2 (33.3%) | 0 |
| BPH | 24 | 18 (75.0%) | 6 (25%) | 0 |
| PCA | 65 | 8 (12.3%) | 25 (38.5%) | 32 (49.2%) |
| Gleason Score | ||||
| 4–5 | 9 | 3 (33.3%) | 6 (66.7%) | 0 |
| 6–7 | 17 | 2 (11.8%) | 11 (64.7%) | 4 (23.5%) |
| 8–9 | 39 | 3 (7.7%) | 8 (20.5%) | 28 (71.8%) |