Table 1.
Drug | Dose | Route of administration | Administered on day(s) | Total dose/cycle |
Carboplatin | AUC 5 | IV | 1 | AUC 5 |
Etoposide | 80-140 mg/m2 | IV | 1-3 | 240-420 mg/m2 |
Cycle repeats: every 3 to 4 weeks | ||||
Variations | ||||
1. Carboplatin AUC 6 IV day 1 and etoposide 100 mg/m2 IV days 1-3 every 3 weeks.9,11 | ||||
2. Carboplatin AUC 5 IV day 1 and etoposide 100 mg/m2 IV days 1-5 every 4 weeks.10 |
Note: AUC = area under the time vs concentration curve; IV = intravenous.